Vitamin E is a family of two groups, Tocopherols and Tocotrienols, which have four isoforms each – Alpha, Beta, Gamma, and Delta. Vitamin E supplement has been recommended for cancer patients to help suppress the growth of cancer and rapid multiplications of cancer cells. Several studies have demonstrated that Tocotrienol based Vitamin E Supplement possesses the most potent anticancer properties.
Tocotrienols: An Overview
This natural vitamin E derivative, Tocotrienol, was discovered in 1956, and its anti-cancer properties were observed in 1985 for the first time. The Tocotrienols have four isomers – Alpha, Beta, Delta, and Gamma. Alpha-Tocotrienol has the highest bioavailability while the Delta and Gamma isoforms of Tocotrienol have the least. The main sources of Tocotrienols include palm oil, rice bran oil, and the annatto plant. The annatto plant is the only source of 100% pure form of Tocotrienols.
Several studies have strongly established Tocotrienol based Vitamin E Supplement as an antioxidant, anti-aging, anti-inflammatory, analgesic, antibacterial, anticancer, anti-diabetic, anti-hyperlipidemic,anti-cholesterolemic,anti-pyretic, anti-thrombotic cardioprotective, chemo-preventive, gastroprotective, hepatoprotective, and neuroprotective agents!
DeltaGold Tocotrienol and it’s Anticancer Properties
Ever since 1985, several studies and research have been conducted on Tocotrienols and it has been observed that all isoforms of Tocotrienols exert anticancer effects on cancer cells of lung, breast, pancreatic, prostate, brain. gastric, skin, liver, and so on. Among the four isoforms, Delta, and Gamma (DeltaGold Tocotrienol), were found to have the most potent anticancer activities.
The following are the unique properties which DeltaGold Tocotrienol possess which help fight cancer:
- Induction of Apoptosis
Apoptosis or programmed cell death is a process by which cancer cells are killed. Tocotrienol based Vitamin E Supplement induce apoptosis in cancer cells, thus suppressing the growth and multiplication of cancer cells.
- Modulation of Cell Cycle Progression
Cell cycle progression is a process by which numerous checks and balances are ensured so that division of cells i.e. proliferation, is a favored outcome. In the case of cancer, the cell cycle progression fails as the cancer cells start multiplying
rapidly. DeltaGold Tocotrienol helps modulate the cell cycle progression and selectively suppresses the division and proliferation of cancer cells.
- Inhibition of Angiogenesis in Cancer Cells
Angiogenesis in cancer is the process by which new and fresh blood vessels are formed in the cancer cells, thus providing nutrition and oxygen to cancer cells, which help sustain their lives. This promotes cancer growth in the individual. Tocotrienols help inhibit angiogenesis selectively in cancer cells and prevent the flow of blood in cancer cells. This process prevents the birth of new cancer cells and also helps in inducing apoptosis in existing cancer cells.
- Prevention of Metastasis
Under metastasis, cancer spreads from its origin to a different body part and affects that region as well. This kind of cancer is also known as Metastatic Cancer. DeltaGold Tocotrienols have been observed to prevent the growth of cancer and suppress metastasis.
In 1985, it was observed that Tocotrienols increased the life span of tumor-bearing rats. It was observed that Tocotrienols suppressed the growth of tumors by killing tumor cells. The process of suppression of the formation or production of tumors is known as anti-tumorigenesis.
- Anti-Inflammatory, Chemopreventive, and Chemotherapeutic Agent
Tocotrienols are one of the most potent, anti-inflammatory, chemopreventive, and chemotherapeutic agents. It is a well-known fact that chronic inflammation leads to several kinds of cancers. Tocotrienols suppress inflammation and hence protect your body from several chronic ailments. Being a chemopreventive agent, DeltaGold Tocotrienols help reduce the risk of development or recurrence of cancer like in the case of recurring ovarian cancer in women. Tocotrienols have been observed to be one of the most potent chemotherapeutic agents as they can combine with several other cytotoxic drugs and inhibit the growth and division of malignant cells during the treatment of cancer.
Several cancers over time, develop chemoresistance against several drugs. Hence, it has always been a matter of concern for researchers to find a novel and effective chemosensitizing agent. Several studies and research have demonstrated that Tocotrienols have great potential when it comes to chemosensitizing cancer cells to therapeutic agents. Several in vivo, and in vitro studies, have revealed that Gamma-Tocotrienol sensitized pancreatic cancer cells to gemcitabine and suppressed the growth of the pancreatic tumor by downregulating the NF-kB pathways.
All the preclinical studies and research have established Tocotrienol based Vitamin E Supplement as safe and novel with incredible health benefits. It has been revealed that Tocotrienols are the “correct” form of Vitamin E and are one of the most potent antioxidant, anti-inflammatory, and anticancer agents.